Rat Strain Differences in Susceptibility to Alcohol-Induced Chronic Liver Injury and Hepatic Insulin Resistance

The finding of more severe steatohepatitis in alcohol fed Long Evans (LE) compared with Sprague Dawley (SD) and Fisher 344 (FS) rats prompted us to determine whether host factors related to alcohol metabolism, inflammation, and insulin/IGF signaling predict proneness to alcohol-mediated liver injury...

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Главные авторы: DeNucci, Sarah M., Tong, Ming, Longato, Lisa, Lawton, Margot, Setshedi, Mashiko, Carlson, Rolf I., Wands, Jack R., de la Monte, Suzanne M.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2010
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931394/
https://ncbi.nlm.nih.gov/pubmed/20814553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/312790
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