Rat Strain Differences in Susceptibility to Alcohol-Induced Chronic Liver Injury and Hepatic Insulin Resistance

The finding of more severe steatohepatitis in alcohol fed Long Evans (LE) compared with Sprague Dawley (SD) and Fisher 344 (FS) rats prompted us to determine whether host factors related to alcohol metabolism, inflammation, and insulin/IGF signaling predict proneness to alcohol-mediated liver injury...

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Hlavní autoři: DeNucci, Sarah M., Tong, Ming, Longato, Lisa, Lawton, Margot, Setshedi, Mashiko, Carlson, Rolf I., Wands, Jack R., de la Monte, Suzanne M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931394/
https://ncbi.nlm.nih.gov/pubmed/20814553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/312790
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