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Optimal drug combinations and minimal hitting sets

BACKGROUND: Identifying effective drug combinations that significantly improve over single agents is a challenging problem. Pairwise combinations already represent a huge screening effort. Beyond two drug combinations the task seems unfeasible. RESULTS: In this work we introduce a method to uncover...

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Bibliografski detalji
Glavni autor: Vazquez, Alexei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738654/
https://ncbi.nlm.nih.gov/pubmed/19660129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-81
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