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A Kernelisation Approach for Multiple d-Hitting Set and Its Application in Optimal Multi-Drug Therapeutic Combinations

Therapies consisting of a combination of agents are an attractive proposition, especially in the context of diseases such as cancer, which can manifest with a variety of tumor types in a single case. However uncovering usable drug combinations is expensive both financially and temporally. By employi...

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Main Authors: Mellor, Drew, Prieto, Elena, Mathieson, Luke, Moscato, Pablo
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956629/
https://ncbi.nlm.nih.gov/pubmed/20976188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013055
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