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Vaccinia Virus CD8(+) T-Cell Dominance Hierarchies Cannot Be Altered by Prior Immunization with Individual Peptides
Heterologous prime-boost is a common vaccination strategy to elicit CD8(+) T cells (T(CD8+)), and vaccinia virus (VACV) has been widely used as a boosting vector. Studies with other viruses have suggested that priming may reduce responses to native epitopes in boosting vectors as well as improve res...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738161/ https://ncbi.nlm.nih.gov/pubmed/19535449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00410-09 |
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