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Surprisingly Effective Priming of CD8(+) T Cells by Heat-Inactivated Vaccinia Virus Virions

Robust priming of CD8(+) T cells by viruses is considered to require infection and de novo expression of viral antigens. A corollary of this is that inactivated viruses are thought of as being inevitably poor vaccines for eliciting these responses. In contrast to this dogma, we found that some antig...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Croft, Sarah, Wong, Yik Chun, Smith, Stewart A., Flesch, Inge E. A., Tscharke, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527048/
https://ncbi.nlm.nih.gov/pubmed/32759313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01486-20
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