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Modified Vaccinia Virus Ankara Can Induce Optimal CD8(+) T Cell Responses to Directly Primed Antigens Depending on Vaccine Design

A variety of strains of vaccinia virus (VACV) have been used as recombinant vaccine vectors with the aim of inducing robust CD8(+) T cell immunity. While much of the pioneering work was done with virulent strains, such as Western Reserve (WR), attenuated strains such as modified vaccinia virus Ankar...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wong, Yik Chun, Croft, Sarah, Smith, Stewart A., Lin, Leon C. W., Cukalac, Tania, La Gruta, Nicole L., Drexler, Ingo, Tscharke, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803277/
https://ncbi.nlm.nih.gov/pubmed/31375596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01154-19
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