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Vaccinia Virus CD8(+) T-Cell Dominance Hierarchies Cannot Be Altered by Prior Immunization with Individual Peptides

Heterologous prime-boost is a common vaccination strategy to elicit CD8(+) T cells (T(CD8+)), and vaccinia virus (VACV) has been widely used as a boosting vector. Studies with other viruses have suggested that priming may reduce responses to native epitopes in boosting vectors as well as improve res...

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Hlavní autoři: Wang, Yang, Flesch, Inge E. A., Tscharke, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738161/
https://ncbi.nlm.nih.gov/pubmed/19535449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00410-09
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