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Safety, Tolerability, and Pharmacokinetics of PA-824 in Healthy Subjects
PA-824 is a novel antibacterial agent that has shown in vitro activity against both drug-sensitive and drug-resistant Mycobacterium tuberculosis. The compound's MIC is between 0.015 and 0.25 μg/ml for drug-sensitive strains and between 0.03 and 0.53 μg/ml for drug-resistant strains. In addition...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737845/ https://ncbi.nlm.nih.gov/pubmed/19528280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00106-09 |
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