Early Bactericidal Activity and Pharmacokinetics of PA-824 in Smear-Positive Tuberculosis Patients

PA-824 is a novel nitroimidazo-oxazine being evaluated for its potential to improve tuberculosis (TB) therapy. This randomized study evaluated safety, tolerability, pharmacokinetics, and extended early bactericidal activity of PA-824 in drug-sensitive, sputum smear-positive, adult pulmonary tubercul...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Diacon, Andreas H., Dawson, Rodney, Hanekom, Madeleine, Narunsky, Kim, Maritz, Stefan J., Venter, Amour, Donald, Peter R., van Niekerk, Christo, Whitney, Karl, Rouse, Doris J., Laurenzi, Martino W., Ginsberg, Ann M., Spigelman, Melvin K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916303/
https://ncbi.nlm.nih.gov/pubmed/20498324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01354-09
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge