A Structure–Activity Relationship Study and Combinatorial Synthetic Approach of C-Terminal Modified Bifunctional Peptides That Are δ/μ Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists

A series of bifunctional peptides with opioid agonist and substance P antagonist bioactivities were designed with the concept of overlapping pharmacophores. In this concept, the bifunctional peptides were expected to interact with each receptor separately in the spinal dorsal horn where both the opi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yamamoto, Takashi, Nair, Padma, Vagner, Josef, Largent-Milnes, Tally, Davis, Peg, Ma, Shou-wu, Navratilova, Edita, Moye, Sharif, Tumati, Suneeta, Lai, Josephine, Yamamura, Henry I., Vanderah, Todd W., Porreca, Frank, Hruby, Victor J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737825/
https://ncbi.nlm.nih.gov/pubmed/18266313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070332f
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak