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Generalized concentration addition: A method for examining mixtures containing partial agonists

Environmentally relevant toxic exposures often consist of simultaneous exposure to multiple agents. Methods to predict the expected outcome of such combinations are critical both to risk assessment and to an accurate judgment of whether combinations are synergistic or antagonistic. Concentration add...

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Bibliographic Details
Main Authors: Howard, Gregory J., Webster, Thomas F.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737481/
https://ncbi.nlm.nih.gov/pubmed/19345693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.03.030
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