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Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas
The tumor predisposition disorder Neurofibromatosis type I (NF1) is one of the most common genetic disorders of the nervous system. It is caused by mutation in the Nf1 tumor suppressor gene, which encodes a GTPase Activating Protein (GAP) that negatively regulates p21-RAS. The development of maligna...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737469/ https://ncbi.nlm.nih.gov/pubmed/19427294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.03.017 |
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