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New insights into the neurofibroma tumor cells of origin
Neurofibromatosis type I (NF1) is a debilitating inherited tumor syndrome affecting around 1 in 3000 people. Patients present with a variety of tumors caused by biallelic loss of the tumor suppressor neurofibromin (NF1), a negative regulator of Ras signaling. While the mechanism of tumor formation i...
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Udgivet i: | Neurooncol Adv |
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Main Authors: | , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Oxford University Press
2019
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7317055/ https://ncbi.nlm.nih.gov/pubmed/32642729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz044 |
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