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New insights into the neurofibroma tumor cells of origin

Neurofibromatosis type I (NF1) is a debilitating inherited tumor syndrome affecting around 1 in 3000 people. Patients present with a variety of tumors caused by biallelic loss of the tumor suppressor neurofibromin (NF1), a negative regulator of Ras signaling. While the mechanism of tumor formation i...

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Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Li, Stephen, Chen, Zhiguo, Le, Lu Q
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317055/
https://ncbi.nlm.nih.gov/pubmed/32642729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz044
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