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Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma

Neurofibromatosis type 1 is a tumor-predisposing genetic disorder. Plexiform neurofibromas are common NF1 tumors carrying a risk of malignant transformation, which is typically fatal. Little is known about mechanisms mediating initiation and identity of specific cell-type that gives rise to neurofib...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Cell
Hauptverfasser: Chen, Zhiguo, Liu, Chiachi, Patel, Amish J., Liao, Chung-Ping, Wang, Yong, Le, Lu Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254535/
https://ncbi.nlm.nih.gov/pubmed/25446898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2014.09.009
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