The role of nerve microenvironment for neurofibroma development

Deregulation of RAS signaling in Neurofibromatosis type 1 (NF1) results in the development of multiple neurofibromas, complex tumor of the peripheral nerves with no effective medical treatment. There is increasing evidences that neurofibroma initiates through loss of NF1 function in the Schwann cell...

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Udgivet i:Oncotarget
Main Authors: Liao, Chung-Ping, Pradhan, Sanjay, Chen, Zhiguo, Patel, Amish J., Booker, Reid C., Le, Lu Q.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308667/
https://ncbi.nlm.nih.gov/pubmed/27517146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11133
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