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Neurofibromas in NF1: Schwann Cell Origin and Role of Tumor Environment

Neurofibromatosis type 1 (NF1) is one of the most prevalent dominantly inherited genetic diseases of the nervous system. NF1 encodes a tumor suppressor whose functional loss results in the development of benign neurofibromas that can progress to malignancy. Neurofibromas are complex tumors composed...

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Detalhes bibliográficos
Main Authors: Zhu, Yuan, Ghosh, Pritam, Charnay, Patrick, Burns, Dennis K., Parada, Luis F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024710/
https://ncbi.nlm.nih.gov/pubmed/11988578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1068452
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