Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

Neurofibromatosis type 1 (NF1) is a prevalent genetic disorder that affects growth properties of neural-crest-derived cell populations. In addition, approximately one-half of NF1 patients exhibit learning disabilities. To characterize NF1 function both in vitro and in vivo, we circumvent the embryon...

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Main Authors: Zhu, Yuan, Romero, Mario I., Ghosh, Pritam, Ye, Zhengyi, Charnay, Patrick, Rushing, Elizabeth J., Marth, Jamey D., Parada, Luis F.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2001
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC312666/
https://ncbi.nlm.nih.gov/pubmed/11297510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.862101
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