Silencing by small RNAs is linked to endosome trafficking

Small RNAs direct RNA induced silencing complexes (RISCs) to regulate the stability and translation of mRNAs1,2. RISCs associated with target mRNAs often accumulate in discrete cytoplasmic foci known as GW-bodies3. However, RISC proteins can associate with membrane compartments such as the Golgi and...

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Autors principals: Lee, Young Sik, Pressman, Sigal, Andress, Arlise P., Kim, Kevin, White, Jamie L., Cassidy, Justin J., Li, Xin, Lubell, Kim, Lim, Do Hwan, Cho, Ik Sang, Nakahara, Kenji, Preall, Jonathan B., Bellare, Priya, Sontheimer, Erik J., Carthew, Richard W.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737091/
https://ncbi.nlm.nih.gov/pubmed/19684574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1930
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