Fenofibrate differentially regulates PAI-1 gene expression via AMPK-dependent induction of orphan nuclear receptor SHP

Plasminogen activator inhibitor type I (PAI-1) is a marker of the fibrinolytic system, and serves as a possible predictor for hepatic metabolic syndromes. Fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, is a drug used for treatments of hyperlipidemia. Orphan nuclear rece...

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Autors principals: Chanda, Dipanjan, Lee, Chul Ho, Kim, Yong-Hoon, Noh, Jung-Ran, Kim, Don-Kyu, Park, Ji-Hoon, Hwang, Jung Hwan, Lee, Mi-Ran, Jeong, Kyeong-Hoon, Lee, In-Kyu, Kweon, Gi Ryang, Shong, Minho, Oh, Goo-Taeg, Chiang, John Y.L., Choi, Hueng-Sik
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737064/
https://ncbi.nlm.nih.gov/pubmed/19593819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23049
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