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Fenofibrate differentially regulates PAI-1 gene expression via AMPK-dependent induction of orphan nuclear receptor SHP
Plasminogen activator inhibitor type I (PAI-1) is a marker of the fibrinolytic system, and serves as a possible predictor for hepatic metabolic syndromes. Fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, is a drug used for treatments of hyperlipidemia. Orphan nuclear rece...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2737064/ https://ncbi.nlm.nih.gov/pubmed/19593819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23049 |
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