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The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy
AMP-activated protein kinase (AMPK) is a crucial energy sensor and plays a key role in integration of cellular functions to maintain homeostasis. Despite this, it is largely unknown whether targeting the AMPK pathway can be used as a therapeutic strategy for infectious diseases. Herein, we show that...
Kaydedildi:
| Yayımlandı: | Autophagy |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5119058/ https://ncbi.nlm.nih.gov/pubmed/24598403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28072 |
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