The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy

AMP-activated protein kinase (AMPK) is a crucial energy sensor and plays a key role in integration of cellular functions to maintain homeostasis. Despite this, it is largely unknown whether targeting the AMPK pathway can be used as a therapeutic strategy for infectious diseases. Herein, we show that...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Yang, Chul-Su, Kim, Jwa-Jin, Lee, Hye-Mi, Jin, Hyo Sun, Lee, Sang-Hee, Park, Ji-Hoon, Kim, Soung Jung, Kim, Jin-Man, Han, Yong-Mahn, Lee, Myung-Shik, Kweon, Gi Ryang, Shong, Minho, Jo, Eun-Kyeong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
Soggetti:
Basic Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119058/
https://ncbi.nlm.nih.gov/pubmed/24598403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28072
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