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How accurate are polymer models in the analysis of Förster resonance energy transfer experiments on proteins?

Single molecule Förster resonance energy transfer (FRET) experiments are used to infer the properties of the denatured state ensemble (DSE) of proteins. From the measured average FRET efficiency, ⟨E⟩, the distance distribution P(R) is inferred by assuming that the DSE can be described as a polymer....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: O’Brien, Edward P., Morrison, Greg, Brooks, Bernard R., Thirumalai, D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Institute of Physics 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736576/
https://ncbi.nlm.nih.gov/pubmed/19334885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3082151
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