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Recognition and discrimination of DNA quadruplexes by acridine-peptide conjugates

We have explored a series of trisubstituted acridine-peptide conjugates for their ability to recognize and discriminate between DNA quadruplexes derived from the human telomere, and the c-kit and N-ras proto-oncogenes. Quadruplex affinity was measured as the peptide sequences were varied, together w...

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Библиографические подробности
Главные авторы: Redman, James E., Granadino-Roldán, J. M., Schouten, James A., Ladame, Sylvain, Reszka, Anthony P., Neidle, Stephen, Balasubramanian, Shankar
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736543/
https://ncbi.nlm.nih.gov/pubmed/19081949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b814682a
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