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Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
Protein damage contributes prominently to cellular aging. To address whether this occurs at a specific period during aging or accumulates gradually, we monitored the biochemical, cellular, and physiological properties of folding sensors expressed in different tissues of C. elegans. We observed the a...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736453/ https://ncbi.nlm.nih.gov/pubmed/19706382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902882106 |
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