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Uncoupling the Trade-Off between Somatic Proteostasis and Reproduction in Caenorhabditis elegans Models of Polyglutamine Diseases

Caenorhabditis elegans somatic protein homeostasis (proteostasis) is actively remodeled at the onset of reproduction. This proteostatic collapse is regulated cell-nonautonomously by signals from the reproductive system that transmit the commitment to reproduction to somatic cells. Here, we asked whe...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Shemesh, Netta, Shai, Nadav, Meshnik, Lana, Katalan, Rotem, Ben-Zvi, Anat
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409330/
https://ncbi.nlm.nih.gov/pubmed/28503130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00101
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