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The Schizosaccharomyces pombe Hsp104 Disaggregase Is Unable to Propagate the [PSI (+)] Prion

The molecular chaperone Hsp104 is a crucial factor in the acquisition of thermotolerance in yeast. Under stress conditions, the disaggregase activity of Hsp104 facilitates the reactivation of misfolded proteins. Hsp104 is also involved in the propagation of fungal prions. For instance, the well-char...

詳細記述

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書誌詳細
主要な著者: Sénéchal, Patrick, Arseneault, Geneviève, Leroux, Alexandre, Lindquist, Susan, Rokeach, Luis A.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736384/
https://ncbi.nlm.nih.gov/pubmed/19759825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006939
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