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The Schizosaccharomyces pombe Hsp104 Disaggregase Is Unable to Propagate the [PSI (+)] Prion
The molecular chaperone Hsp104 is a crucial factor in the acquisition of thermotolerance in yeast. Under stress conditions, the disaggregase activity of Hsp104 facilitates the reactivation of misfolded proteins. Hsp104 is also involved in the propagation of fungal prions. For instance, the well-char...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736384/ https://ncbi.nlm.nih.gov/pubmed/19759825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006939 |
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