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New Sources of Chemical Diversity Inspired by Biosynthesis: Rational Design of a Potent Epothilone Analogue
[Image: see text] A concise total synthesis of S-14-methoxy-epothilone D has been accomplished. S-14-Methoxy-epothilone D represents a conceptually novel example of polyketide analogue design based on an alternative biogenetic pattern of extender units. The significant biological activity observed f...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736359/ https://ncbi.nlm.nih.gov/pubmed/19572566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol900971r |
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