Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes

BACKGROUND: Guanine-rich nucleic acid sequences are capable of folding into an intramolecular four-stranded structure called a G-quadruplex. When found in gene promoter regions, G-quadruplexes can downregulate gene expression, possibly by blocking the transcriptional machinery. Here we have used a g...

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Main Authors: Smargiasso, Nicolas, Gabelica, Valérie, Damblon, Christian, Rosu, Frédéric, De Pauw, Edwin, Teulade-Fichou, Marie-Paule, Rowe, J Alexandra, Claessens, Antoine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736202/
https://ncbi.nlm.nih.gov/pubmed/19660104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-362
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