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G-Quadruplex DNA Motifs in the Malaria Parasite Plasmodium falciparum and Their Potential as Novel Antimalarial Drug Targets

G-quadruplexes are DNA or RNA secondary structures that can be formed from guanine-rich nucleic acids. These four-stranded structures, composed of stacked quartets of guanine bases, can be highly stable and have been demonstrated to occur in vivo in the DNA of human cells and other systems, where th...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Harris, Lynne M., Monsell, Katelyn R., Noulin, Florian, Famodimu, M. Toyin, Smargiasso, Nicolas, Damblon, Christian, Horrocks, Paul, Merrick, Catherine J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826154/
https://ncbi.nlm.nih.gov/pubmed/29311059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01828-17
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