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Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes
BACKGROUND: Guanine-rich nucleic acid sequences are capable of folding into an intramolecular four-stranded structure called a G-quadruplex. When found in gene promoter regions, G-quadruplexes can downregulate gene expression, possibly by blocking the transcriptional machinery. Here we have used a g...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736202/ https://ncbi.nlm.nih.gov/pubmed/19660104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-362 |
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