Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes

BACKGROUND: Guanine-rich nucleic acid sequences are capable of folding into an intramolecular four-stranded structure called a G-quadruplex. When found in gene promoter regions, G-quadruplexes can downregulate gene expression, possibly by blocking the transcriptional machinery. Here we have used a g...

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Bibliografiske detaljer
Main Authors:	Smargiasso, Nicolas, Gabelica, Valérie, Damblon, Christian, Rosu, Frédéric, De Pauw, Edwin, Teulade-Fichou, Marie-Paule, Rowe, J Alexandra, Claessens, Antoine
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2009
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2736202/ https://ncbi.nlm.nih.gov/pubmed/19660104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-362
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Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes

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