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Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice

Genetic instability, which leads to an accumulation of various genetic abnormalities, has been considered an essential component of the human neoplasic transformation process. However, the molecular basis of genomic instability during tumorigenesis remains incompletely understood. Growing evidence i...

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Detalhes bibliográficos
Main Authors: Fu, Zheng, Regan, Kevin, Zhang, Lizhi, Muders, Michael H., Thibodeau, Stephen N., French, Amy, Wu, Yanhong, Kaufmann, Scott H., Lingle, Wilma L., Chen, Junjie, Tindall, Donald J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735912/
https://ncbi.nlm.nih.gov/pubmed/19690386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37405
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