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Enhanced Excitation-Coupled Calcium Entry in Myotubes Expressing Malignant Hyperthermia Mutation R163C Is Attenuated by Dantrolene

Dantrolene is the drug of choice for the treatment of malignant hyperthermia (MH) and is also useful for treatment of spasticity or muscle spasms associated with several clinical conditions. The current study examines the mechanisms of dantrolene's action on skeletal muscle and shows that one o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cherednichenko, Gennady, Ward, Chris W., Feng, Wei, Cabrales, Elaine, Michaelson, Luke, Samso, Montserrat, López, José R., Allen, Paul D., Pessah, Isaac N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735873/
https://ncbi.nlm.nih.gov/pubmed/18171728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.043299
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