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Optimized Bacterial Expression and Purification of the c-Src Catalytic Domain for Solution NMR Studies

Progression of a host of human cancers is associated with elevated levels of expression and catalytic activity of the Src family of tyrosine kinases (SFKs), making them key therapeutic targets. Even with the availability of multiple crystal structures of active and inactive forms of the SFK catalyti...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Piserchio, Andrea, Ghose, Ranajeet, Cowburn, David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735562/
https://ncbi.nlm.nih.gov/pubmed/19399371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-009-9318-y
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