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The Rho-Guanine Nucleotide Exchange Factor Domain of Obscurin Activates RhoA Signaling in Skeletal Muscle

Obscurin is a large (∼800-kDa), modular protein of striated muscle that concentrates around the M-bands and Z-disks of each sarcomere, where it is well positioned to sense contractile activity. Obscurin contains several signaling domains, including a rho-guanine nucleotide exchange factor (rhoGEF) d...

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Bibliografiset tiedot
Päätekijät: Ford-Speelman, Diana L., Roche, Joseph A., Bowman, Amber L., Bloch, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2009
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735489/
https://ncbi.nlm.nih.gov/pubmed/19605563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-10-1029
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