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The Rho-Guanine Nucleotide Exchange Factor Domain of Obscurin Regulates Assembly of Titin at the Z-Disk through Interactions with Ran Binding Protein 9

Obscurin is an ∼800-kDa protein composed of structural and signaling domains that organizes contractile structures in striated muscle. We have studied the Rho-GEF domain of obscurin to understand its roles in morphogenesis and signaling. We used adenoviral overexpression of this domain, together wit...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bowman, Amber L., Catino, Dawn H., Strong, John C., Randall, William R., Kontrogianni-Konstantopoulos, Aikaterini, Bloch, Robert J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Cell Biology 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526693/
https://ncbi.nlm.nih.gov/pubmed/18579686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-03-0237
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