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The role of phagosomal pH on the size-dependent efficiency of cross-presentation by dendritic cells

Vaccines able to stimulate CD8(+)T cells are crucial in controlling a broad range of infectious diseases and tumors. To induce effective CD8(+)T cell responses, exogenous antigen has to be cross-presented onto major histocompatibility complex (MHC) class I molecules by dendritic cells. Although part...

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Detalhes bibliográficos
Main Authors: Tran, Kenny K., Shen, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735406/
https://ncbi.nlm.nih.gov/pubmed/19091401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.11.034
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