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Synthesis of 3-Sulfenyl- and 3-Selenylindoles by the Pd/Cu-Catalyzed Coupling of N,N-Dialkyl-2-iodoanilines and Terminal Alkynes, Followed by n-Bu(4)NI-Induced Electrophilic Cyclization

[Image: see text] 3-Sulfenyl- and 3-selenylindoles are readily synthesized by a two-step process involving the palladium/copper-catalyzed crossing coupling of N,N-dialkyl-ortho-iodoanilines and terminal alkynes and subsequent electrophilic cyclization of the resulting N,N-dialkyl-ortho-(1-alkynyl)an...

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Detalhes bibliográficos
Main Authors: Chen, Yu, Cho, Chul-Hee, Shi, Feng, Larock, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735226/
https://ncbi.nlm.nih.gov/pubmed/19663396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9014003
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