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Ca/Calmodulin Kinase II Differentially Modulates Potassium Currents

BACKGROUND: Potassium currents contribute to action potential duration (APD) and arrhythmogenesis. In heart failure, Ca/calmodulin-dependent protein kinase II (CaMKII) is upregulated and can alter ion channel regulation and expression. METHODS AND RESULTS: We examine the influence of overexpressing...

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Main Authors: Wagner, Stefan, Hacker, Elena, Grandi, Eleonora, Weber, Sarah L., Dybkova, Nataliya, Sossalla, Samuel, Sowa, Thomas, Fabritz, Larissa, Kirchhof, Paulus, Bers, Donald M., Maier, Lars S.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734104/
https://ncbi.nlm.nih.gov/pubmed/19808479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.108.842799
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