Pharmacodynamic/Pharmacogenomic Modeling of Insulin Resistance Genes in Rat Muscle After Methylprednisolone Treatment: Exploring Regulatory Signaling Cascades

Corticosteroids (CS) effects on insulin resistance related genes in rat skeletal muscle were studied. In our acute study, adrenalectomized (ADX) rats were given single doses of 50 mg/kg methylprednisolone (MPL) intravenously. In our chronic study, ADX rats were implanted with Alzet mini-pumps giving...

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Main Authors: Yao, Zhenling, Hoffman, Eric P., Ghimbovschi, Svetlana, DuBois, Debra C., Almon, Richard R., Jusko, William J.
格式: Artigo
語言:Inglês
出版: Libertas Academica 2008
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Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733097/
https://ncbi.nlm.nih.gov/pubmed/19787081
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