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Determining the catalytic role of remote substrate binding interactions in ketosteroid isomerase

A fundamental difference between enzymes and small chemical catalysts is the ability of enzymes to use binding interactions with nonreactive portions of substrates to accelerate chemical reactions. Remote binding interactions can localize substrates to the active site, position substrates relative t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schwans, Jason P., Kraut, Daniel A., Herschlag, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732871/
https://ncbi.nlm.nih.gov/pubmed/19706511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901032106
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