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Uncovering the Determinants of a Highly Perturbed Tyrosine pK(a) in the Active Site of Ketosteroid Isomerase()
Within the idiosyncratic enzyme active site environment, side chain and ligand pK(a) values can be profoundly perturbed relative to their values in aqueous solution. Whereas structural inspection of systems has often attributed perturbed pK(a) values to dominant contributions from placement near to...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2013
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3890242/ https://ncbi.nlm.nih.gov/pubmed/24151972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401083b |
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