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Determining the catalytic role of remote substrate binding interactions in ketosteroid isomerase

A fundamental difference between enzymes and small chemical catalysts is the ability of enzymes to use binding interactions with nonreactive portions of substrates to accelerate chemical reactions. Remote binding interactions can localize substrates to the active site, position substrates relative t...

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Detalhes bibliográficos
Main Authors: Schwans, Jason P., Kraut, Daniel A., Herschlag, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732871/
https://ncbi.nlm.nih.gov/pubmed/19706511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901032106
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