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Rational engineering of type II restriction endonuclease DNA binding and cleavage specificity

The type II restriction endonucleases are indispensible tools for molecular biology. Although enzymes recognizing nearly 300 unique sequences are known, the ability to engineer enzymes to recognize any sequence of choice would be valuable. However, previous attempts to engineer new recognition speci...

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Bibliografski detalji
Glavni autori: Morgan, Richard D., Luyten, Yvette A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731914/
https://ncbi.nlm.nih.gov/pubmed/19567736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp535
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