15-Epi-lipoxin A(4) Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

Rationale: Apoptosis is essential for removal of neutrophils from inflamed tissues and efficient resolution of inflammation. Myeloperoxidase (MPO), abundantly expressed in neutrophils, not only generates cytotoxic oxidants but also signals through the β(2) integrin Mac-1 to rescue neutrophils from c...

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Main Authors: El Kebir, Driss, József, Levente, Pan, Wanling, Wang, Lili, Petasis, Nicos A., Serhan, Charles N., Filep, János G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Thoracic Society 2009
Ábhair:
B. Critical Care
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731808/
https://ncbi.nlm.nih.gov/pubmed/19483113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200810-1601OC
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