15-Epi-lipoxin A(4) Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

Rationale: Apoptosis is essential for removal of neutrophils from inflamed tissues and efficient resolution of inflammation. Myeloperoxidase (MPO), abundantly expressed in neutrophils, not only generates cytotoxic oxidants but also signals through the β(2) integrin Mac-1 to rescue neutrophils from c...

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Главные авторы: El Kebir, Driss, József, Levente, Pan, Wanling, Wang, Lili, Petasis, Nicos A., Serhan, Charles N., Filep, János G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2009
Предметы:
B. Critical Care
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731808/
https://ncbi.nlm.nih.gov/pubmed/19483113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200810-1601OC
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