15-Epi-lipoxin A(4) Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

Rationale: Apoptosis is essential for removal of neutrophils from inflamed tissues and efficient resolution of inflammation. Myeloperoxidase (MPO), abundantly expressed in neutrophils, not only generates cytotoxic oxidants but also signals through the β(2) integrin Mac-1 to rescue neutrophils from c...

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Main Authors: El Kebir, Driss, József, Levente, Pan, Wanling, Wang, Lili, Petasis, Nicos A., Serhan, Charles N., Filep, János G.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2009
Assuntos:
B. Critical Care
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731808/
https://ncbi.nlm.nih.gov/pubmed/19483113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200810-1601OC
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