15-Epi-lipoxin A(4) Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

Rationale: Apoptosis is essential for removal of neutrophils from inflamed tissues and efficient resolution of inflammation. Myeloperoxidase (MPO), abundantly expressed in neutrophils, not only generates cytotoxic oxidants but also signals through the β(2) integrin Mac-1 to rescue neutrophils from c...

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Detalhes bibliográficos
Main Authors: El Kebir, Driss, József, Levente, Pan, Wanling, Wang, Lili, Petasis, Nicos A., Serhan, Charles N., Filep, János G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
B. Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731808/
https://ncbi.nlm.nih.gov/pubmed/19483113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200810-1601OC
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